Announcements

How Proteins Remodel DNA in Bacteria under Stress

ALS-ENABLE beamlines use multiscale, multimodal visualization techniques to clarify how proteins remodel bacterial DNA in response to stressful environments. At the mesoscale, small-angle x-ray scattering (SAXS) at Beamline 12.3.1 made…
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Congratulations to Jennifer Doudna!

A huge congratulations to the team of Doudna and Charpentier who received the Nobel Prize in Chemistry this year for the development of a new method of genome editing, namely, the much used CRISPR system. Dounda did much of her early structural work on this system using several of the ALS-ENABLE beamlines (though at the time these beamlines were not banded together under the ALS-ENABLE umbrella). We are very proud! Here is a link to a list of publications resulting from work at our beamlines.

SIBYLS BioSAXS workshop goes virtual!

Even though we had to hold our BioSAXS workshop virtually this year, it turned out to be one of our best ever. We had more 70 participants over the two…
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Free SIBYLS BioSAXS Workshop August 27 and 28, 2020

The SIBYLS group is holding a virtual workshop and tutorial during the ALS User Meeting. This workshop is designed for current and future SIBYLS and ALS-ENABLE users. We will provide…
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Bioimaging Forum

Members of the ALS-ENABLE team helped organize a Bioimaging Forum to discuss current and future bioimaging methods and science at Berkeley Lab. This is the first in a series of…
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X-ray Footprinting Workshop at the ACA Conference

At the ALS, X-ray Footprinting is a structural biology method that is available to users on beamline 3.2.1. Although X-ray Footprinting is not currently funded through ALS-ENABLE, the method serves…
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Protein Sculpts DNA to Repair Harmful Damage

In this study, small angle X-ray scattering (SAXS) at ALS-ENABLE beamline 12.3.1 of Berkeley Lab’s Advanced Light Source was used to see the shapes of individual DNA molecules providing an…
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COVID-19 Research at ALS-ENABLE

ALS-ENABLE are among a limited number of beamlines at the ALS given approval for operation during the current Bay Area shelter-in-place orders. We are open for all your research needs;…
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BL 12.3.1 has a new flight tube

SIBYLS installed a new flight tube at BL 12.3.1 giving us 2 meters distance from beam to detector allowing for wider angle capture. If you are interested in sending samples for collection go to our mail-in website to book a slot